Question

For each reaction between a ketone and an amine, draw the curved arrow(s) to show the first step of the mechanism, then draw the final organic product. (If you accidentally changed the structures given in the problem, click on the red over/under arrows to remove any changes you have made.

Answer 1

The first step in the mechanism between a ketone and an amine is the nucleophilic addition of the amine to the carbonyl carbon of the ketone, followed by the elimination of a water molecule to form an imine.

Step-by-step explanation:

The reaction between a ketone and an amine involves the formation of an imine. The first step of the mechanism is the nucleophilic addition of the amine to the carbonyl carbon of the ketone. This is followed by the elimination of a water molecule, resulting in the formation of the imine product.

Here is the step-by-step process:

1. Draw the ketone and the amine.
2. Identify the carbonyl carbon in the ketone. Draw a curved arrow from the lone pair of electrons on the nitrogen of the amine to the carbonyl carbon.
3. Label the intermediate with a positive charge on the nitrogen and a negative charge on the oxygen of the carbonyl.
4. Draw a curved arrow from the oxygen of the carbonyl to the nitrogen, breaking the double bond and forming a water molecule.
5. Draw the final imine product.