Question

Under starvation conditions cells deaminate amino acids to produce carbon skeletons that enter the glycolytic pathway and the citric acid cycle to generate ATP. Nucleotides, on the other hand, are not broken down to yield energy. Select the statements that describe how cells metabolize nucleotides. a.Free bases released from nucleotide degradation are often reused for nucleotide synthesis. b.Nucleotides are hydrolyzed into ribose and nitrogenous bases. c.Purines are further metabolized to uric acid and pyrimidine degradation produces urea. d.Free bases from hydrolysis of nucleotides are further degraded into their amino acid precursors, glycine and aspartate. e.Although nucleotides can be hydrolyzed to release purine or pyrimidine bases, most organisms lack the enzymes to further degrade the free bases. Instead, free purine and pyrimidine bases are secreted into the bloodstream. During de novo synthesis of nucleotides, free bases released from degradation of nucleotides are attached to ribose.

Answer 1

Option a, b and c

Step-by-step explanation:

Free bases released from nucleotide degradation are often reused for nucleotide synthesis

Nucleotides are hydrolyzed into ribose and nitrogenous bases.

Purines are further metabolized to uric acid and pyrimidine degradation produces urea