Question

Which one of the following enzymes and intermediates is not a part of the energy investment stage of glycolysis:aldolaseDHAP (dihydroxy acetone phosphate)PFK-1 (phosphofructokinase-1)GAPDH (glyceraldehyde-3-phosphate dehydrogenase)Fructose-6-phosphate (F6P)Phosphohexose isomerase

Answer 1

GAPDH (glyceraldehyde-3-phosphate dehydrogenase)

Step-by-step explanation:

The first half of glycolysis is the energy investment stage. While the second half of glycolysis is the energy releasing stage, i.e 4 ATP molecules and 2 NADPH molecules are released.

Of all the above mentioned enzymes, glyceraldehyde 3 phosphate dehydrogenase is not involved in energy investment stage, rather it is required in the energy releasing steps;

glyceraldehyde-3-phosphate dehydrogenase catalyses the oxidation of the sugar glyceraldehyde-3-phosphate. This step produces NADPH. The sugar is then phosphorylated by the addition of a second phosphate group, producing 1,3-bisphosphoglycerate.