Question

The Binding Immunoglobulin Protein (BiP) is a molecular chaperone that is essential for the translocation of secreted peptides into the lumen of the ER. Because it is a chaperone, it is important for ______

Answer 1

Answer: Protein folding and oligomerization

Step-by-step explanation:

Binding immunoglobulin protein (BiP) is a vital protein present in humans essential for the translocation of secreted peptides.

BiP is a molecular chaperone which is present in lumen of ER (endoplasmic reticulum) which binds to the new protein and then translocat into the ER. The protein in ER is maintained under subsequent condition and important for protein folding and oligomerization (conversion of a monomer or group of monomer into an oligomer).

Several other functions of BiP are:

1. ER translocation
2. ER-associated degradation (ERAD)
3. UPR pathway

Hence, BiP is a chaperone, it is important for protein folding and oligomerization.