Answer:
HIE, HIO
Step-by-step explanation:
These are the two words that best fill the blanks. HIE stands for "Health Information Exchange." This is a system of the U.S. Department of Health and Human Services. HIE allows for different organizations to have access to information related to health in order to provide better care.
On the other hand, HIO refers to a "Health Information Exchange Organization". This is an organization that controls the exchange of information among various organizations. This means that a HIO's purpose is to provide oversight for HIEs.