One trait that protects people from Malaria is Sickle Cell Anemia. The infected cells collapse when plasmodium tries to feed off them and prevents them from getting actin proteins. It guards the host from Malaria.
Another trait is people that are negative for the Duffy blood group have resistance to infections caused by p. vivax (plasmodium vivax).
Hope this helps, if there is anything else I can help you with, just drop a comment!