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Proton-pump inhibitors are drugs that block the secretions of gastric acids. Which cells are affected by these drugs?

User Darwin
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Answer: Parietal cells

Step-by-step explanation:

Parietal cells secrete hydrochloric acid in the stomach. They are also known as oxyntic cells. They are the epithelial cells which is located in the gastric glands found in the lining of the fundus and cardia of the stomach.

The proton pump blocks the hydrogen ion pump in the parietal cells. These drugs are commonly known by the name of omeprazole.

They block the the H+/K+ ATPase proton pump which inturn inhibits both basal and stimulated secretion of the gastric acid from the cells.

User Tom Russell
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