Question

Why are irreversible enzyme inhibitors often called poisons? Select all that apply. (I thought it was all of them but apparently not.)

1. Thye resemble the natural substrate of an enzyme.
2. They disrupt normal cellular metabolism.
3. They can cause sickness and death.
4. They do permanent damage to many types of enzymes.

Answer 1

4. They do permanent damage to many types of enzymes

Step-by-step explanation:

Irreversible enzyme inhibitors are poisons. They cause permanent damage to many different types of enzymes.

These inhibitors slows down reactions and disrupt the activities of normal cell metabolism. They can lead to a wide range of diseases.

• Irreversible enzymes inhibitors binds covalently to another enzyme and it thwarts their normal activities.
• They assume the shape of normal substrates