When you have a negative exponent, you move the variable with the negative exponent to the other side of the fraction to make the exponent positive.
For example:
or x³
or

When you multiply a variable with an exponent by a variable with an exponent, you add the exponents together. (The variables have to be the same in order to combine them)
For example:
(The variables(x and y) are different, so you can't combine them)

or y²
First make all the exponents positive


(This is as far as you can simplify)