Plasma cells ________. Plasma cells ________. are small so that they slip between endothelial cells of capillaries to fight infection in the surrounding tissues have a great deal of rough endoplasmic reticulum to dispose of ingested pathogens have a great deal of rough endoplasmic reticulum reflecting the fact that they secrete a tremendous amount of protein (antibody) are large so that they can envelope their prey by phagocytosis