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Plasma cells ________. Plasma cells ________. are small so that they slip between endothelial cells of capillaries to fight infection in the surrounding tissues have a great deal of rough endoplasmic reticulum to dispose of ingested pathogens have a great deal of rough endoplasmic reticulum reflecting the fact that they secrete a tremendous amount of protein (antibody) are large so that they can envelope their prey by phagocytosis

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The correct answer is: Statement 3, (have a great deal.........protein (antibody).

Step-by-step explanation:

  • Plasma cells are also known as Plasma B cells.
  • They are one of the types of white blood cells which develop inside the bone marrow.
  • Inside the bone marrow are present the multipotent hematopoetic stem cells.
  • These cells differentiate to form the myeloid stem cells and the lymphoid stem cells.
  • The lymphoid stem cells develop into the lymphoblasts which further differentiate to form the B lymphocytes, T lymphocytes and Natural Killer cells respectively.
  • The B lymphocytes form the plasma cells.
  • These plasma cells produce antibodies which target foreign materials or organisms and tag them to be recognized and destroyed by other cells of the immune system like macrophages, T cells, Natural Killer cells, etc.
  • The antibodies are composed of proteins.
  • Hence, in order to produce huge amounts of antibodies (proteins) the B cells have huge quantity of rough endoplasmic reticulum (RER).
  • This is because secretory proteins or proteins present in the plasma membrane are synthesized by the ribosomes attached to the endoplasmic reticulum (ER), that is, the RER.
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