(16^3 + 16x^2 + 19x + 12) / (4x + 3). Start by factoring the numerator.
(4x + 3) (4x^2 + x + 4) / (4x + 3). Since (4x + 3) is a term in both the numerator and the denominator, we can cancel them out.
You're left with: 4x^2 + x + 4.
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