Question

Many cases of severe combined immunodeficiency result from mutations in adenosine deaminase (an enzyme involved in nucleic acid turnover). Deficiency of this enzyme's activity leads to a 100-fold increase in dATP, yet also causes a deficiency in dNTPs required by lymphocytes for replication and proper immune function. Explain.

Answer 1

The deficiency in dNTPs is typically caused as a result of mutations such as changes in the adenosine deaminase gene . The adenosine deaminase gene is vital for the production of enzymes commonly found in lymphocytes. The lymphocytes are vital components of the body immune system that fight infections and keep the body healthy.

Step-by-step explanation:

The deficiency in dNTPs is typically caused as a result of mutations such as changes in the adenosine deaminase gene . The adenosine deaminase gene is vital for the production of enzymes commonly found in lymphocytes. The lymphocytes are vital components of the body immune system that fight infections and keep the body healthy.