Answer: increasing sickle-cell allele frequency
Step-by-step explanation:
Sickle cell anemia is the most common inherited blood disorder in the United States. In the United States, approximately 100,000 people have SCD. SCD occurs in about 1 of every 16,300 Hispanic-American births. Approximately 1 in 13 black or African Americans has sickle cell trait.
Sickle cell disease (SCD) affects millions of people throughout the world and is particularly common among those whose ancestors came from sub-Saharan Africa; Spanish-speaking regions in the Western Hemisphere (South America, the Caribbean, and Central America); Saudi Arabia; India; and Mediterranean countries such as Turkey, Greece, and Italy.