Question

A 35-year-old man presents with anemia, neutropenia, thrombocytopenia, myeloblasts with the presence of Auer rods, and one or two distinct nucleoli and promyelocytes. Cytochemistry examination demonstrates peroxidase and Sudan black B (SBB) positive and TdT terminal eoxynucleotidyl transferase (TdT) negative. This hematologic picture is consistent with: A) Acute lymphoblastic leukemia (ALL) B) Acute myeloblastic leukemia (AML) C) Chronic myelocytic leukemia (CML) D) Chronic lymphocytic leukemia (CLL) E) None of the above

Answer 1

Answer: The hematologic picture is consistent with Acute myeloblastic leukemia (AML). Therefore the correct option is B.

Step-by-step explanation:

Leukaemia is a type of cancer that affects the blood forming tissues such as the bone marrow, leading to excessive or over production of abnormal blood cells ( usually the white blood cells). They occur in two categories; it can be Acute leukaemia or Chronic leukaemia.

There are different forms of acute leukaemia which is classified according to the lineage ( myeloid or lymphoid). They include:

- Acute Myeloblastic Leukaemia (AML)and

- Acute Lymphoblastic Leukaemia ( ALL).

In AML, the following Laboratory diagnosis differentiates it from other leukaemia, these includes:

- myeloblasts with the presence of Auer rods, and one or two distinct nucleoli and promyelocytes, and

-peroxidase and Sudan black B (SBB) positive and TdT terminal eoxynucleotidyl transferase (TdT) negative. Therefore the correct option is B

Answer 2

B) Acute myeloblastic leukemia (AML

Step-by-step explanation:

It is a type of cancer that affects the blood as well as the bone marrow. It causes a situation whereby there is excessive immature white blood cells thus affecting the production of matured or normal white and red blood cells, blood platelets through the interference of the myeloid cells.

It is treatable medical condition that requires medical diagnosis. It requires laboratory tests with imaging always needed. It is also known as Acute myelogenous leukemia, acute granulocytic leukemia and acute nonlymphocytic leukemia.