Question

Sick cell disease (SCD) primarily affects: A. children of African descent and Hispanics of Caribbean ancestry. B. children of Middle-Eastern and Indian descent. C. children of Asian descent. D. both African descent and Hispanics of Caribbean ancestry and Middle-Eastern and Indian descent.

Answer 1

Sick cell disease (SCD) primarily affects:both African descent and Hispanics of Caribbean ancestry and Middle-Eastern and Indian descent. Correct option is D.

Step-by-step explanation:

Sickle cell disease is a sickle cell disorder in which the red cells become sickel- shaped when there are subjected to low oxygen tension. The clinical manifestations usually develops 3 to 4 months of age when the level of HbF ( foetal haemoglobin) falls and they include:

- impaired growth and development,

- splenomegaly,

- infection( due to impaired slpenic phagocytic function) and

- vaso- occlusive crises.

Sickle cell disease is divided into the following types:

- sickle cell anaemia

-Sickle cell B thalassemia.

The prevalence of SCD is worldwide with the different types occurring more in specific regions. Therefore option D is correct.

Answer 2

The correct answer is D

Step-by-step explanation:

Sickle cell anemia is a genetic disease of the red blood cells. It is an inherited red blood cell disorder that affects hemoglobin, the molecule in red blood cells that delivers oxygen to cells throughout the body. Sickle cell disease primarily affects children of African descent and Hispanics of Caribbean ancestry and children of Middle-Eastern and Indian descent.