Final answer:
During the contraction of heart muscle cells, some extracellular calcium enters the cell and triggers the release of additional calcium from the sarcoplasmic reticulum, which is essential for cardiac muscle contraction.
Step-by-step explanation:
During contraction of heart muscle cells some calcium enters the cell from the extracellular space and triggers the release of larger amounts of calcium from intracellular stores. This process is known as the calcium-induced calcium release (CICR) mechanism, which is essential for the contraction of cardiac muscles. The initial influx of calcium through the slow calcium channels during the action potential depolarization phase, accounts for a small portion (approximately 20%) of the calcium required for contraction. The majority of the calcium used in contraction is then released from the sarcoplasmic reticulum (SR).
Unlike skeletal muscle, where almost all of the calcium comes from the SR, cardiac muscle fibers rely on both the influx of extracellular calcium and the release from the SR to initiate contraction. This mechanism allows for a longer contraction time in cardiac muscles, which is necessary for the proper functioning of the heart.