Question

A student is studying cotranslational import into the ER lumen in a cell-free system. What would be the expected result if the student were to replace all of the GTP in the system with a nonhydrolyzable analog of GTP?

A) The SRP/SRP receptor complex would never allow translation to resume.
B) The SRP would remain bound to the SRP receptor on the ER surface.
C) The ribosome would never dock with the ribosome receptor on the ER surface.
D) The SRP would never bind to the SRP receptor.

Answer 1

Answer:B. The SRP would remain bound to the SRP receptor on the ER surface.

Explanation:Cotranslation is the process through which protein production or synthesis is closely coupled with the translocation of the growing protein to the specific location within the cell of an organism like through endoplasmic reticulum (rER) and plasma membranes.

GTP(GUANOSINE TRIPHOSPHATE) is similar to ATP, it is essential for the synthesis of proteins, it contains A GUANINE MOLECULE, THREE PHOSPHATE MOLECULAR GROUP AND A RIBOSE, IT IS ONE OF THE BUILDING BLOCKS OF RIBONUCLEIC ACID(RNA).