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How does HbS aggregation occur in sickle‑cell anemia? Place the steps in the correct order. Note that deoxyhemoglobin is in the T state; oxyhemoglobin is in the R state.

User Will Stone
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Sickle cell Anemia

Step-by-step explanation:

  • Sickle cell anemia (sickle cell sickness) is a confusion of the blood caused about by an acquired unusual hemoglobin (the oxygen-conveying protein inside the red platelets)
  • The irregular hemoglobin causes mutilated red platelets.
  • Bisphosphoglycerate, or BPG, is one of numerous allosteric controllers for hemoglobin
  • This atom ties to the focal hole of the deoxy hemoglobin rendition of hemoglobin (T-state) and balances out it.
  • Hemoglobin is the oxygen-moving protein of red platelets and is a globular protein with a quaternary structure
  • There are two states in the hemoglobin, the T express (the strained state) and the R express (the casual state). The T state has less of a proclivity for oxygen than the R state.
User Marijne
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