Question

You are comparing two peptides translated in two different cells. The peptide has an identical primary structure, but there is much less of the peptide produced in one of the cells. Which of the following is a potential explanation?

a. an alternative polyA addition site was selected in one of the cells

b. the length of the polyA tail is different in the two cells

c. Alternative splicing was used

d. A and B are both correct.

Answer 1

Length of PolyA tail is different in two cells

Step-by-step explanation:

• Different lengths of Poly A tails are present for different mRNAs so when we compare two peptides translated in two different cells we have different lengths of PolyA tail

• PolyA tail is basically a long chain of nucleotides(adenine nucleotides) which are added to messenger RNA(mRNA) during processing of RNA
• It increases the stability of the molecule
• It protects the mRNA molecule from undergoing degradation in the cytoplasm
• It is involved in binding proteins which further initiates translation;introns are removed from pre mRNA before the final mRNA is exported into cytoplasm