Answer:
(A). epithelial tissue.
Step-by-step explanation:
Angiogenesis inhibitors can be defined as anti-cancer drugs that inhibit growth and development of newly formed blood vessels around tumors.
These drugs are used in cancer treatment of various types of cancer. This is because, most of the cells receive nutrients and oxygen from blood supply and these drugs cut off the blood supply to tumorous cells.
However, angiogenesis inhibitors would be least effective for treatment of tumors in epithelial tissue as epithelial tissues do to not have blood vessels. These tissue receive nutrients and oxygen from tissue present beneath the epithelial cells.
Thus, the correct answer is option (A).