Answer:
The cytoplasm of the cell is all the material outside of the nucleus. On occasion, it is necessary to distinguish between the cytosol and the cytoplasm. The cytosol is defined as all the material in the cytoplasm, excluding the contents of the various membranous organelles. The cytosol, therefore, does include the cytoskeleton, the ribosomes, and the centrosome, together with all the other macromolecules and solutes outside the nucleus and also outside the lumen of the various cytoplasmic membranous organelles (mitochondria, ER, Golgi, transport vesicles, endosomes, and so forth).