Question

An illness that results from a malfunction of the red blood cell because of an incorrect structure in parts of the hemoglobin protein chain is called _______________.

Answer 1

Answer:Sickle cell

Explanations:

The mutation in the HBB gene in sickle cell anemia changes one of the amino acids, the building blocks of proteins, in the beta chain of hemoglobin. This defect causes the hemoglobin protein to stick together and form stiff fibers. These fibers distort the shape of the red blood cells and make them more fragile.

Answer 2

Answer: Sickle-cell disease

Step-by-step explanation:

Sickle-cell disease is characterized by the presence of a sickle shaped red blood cell, due to the substitution of glutamate with valine in the amino acid sequence of the protein globin portion.

Hence, the sickled shaped globin is unable to transport oxygen efficiently to body tissues, resulting in malfunction of the red blood cell.