Answer:
cell samples
methods to observe the effects of climate on gene mutations
Step-by-step explanation:
Epigenetics can be described as the field of genetics under which those heritable phenotype characteristics are studied which are not influenced by alternations in the genetic makeup or DNA sequence of the individual.
As altered gene sequences and genetic diseases depend on the changes in the DNA hence, option A and D are not correct.
Cell sample and studying the effects of climate on gene mutations are not related to the alternation of DNA and hence are correct options.