Answer:
A
Step-by-step explanation:
Endocrine hormone are secreted into the blood and carried by blood and tissue fluids to the cells they act upon, while exocrine hormones are secreted into a duct, and then into the bloodstream. Exocrine hormones are transferred from cell to cell by diffusion (paracrine signaling).
Hormones are typically secreted into systemic circulation. However, some are secreted into portal systems that allow for direct hormone targeting.
Hormones can exist freely in systemic circulation, but the majority are bound with transport proteins.
Transport proteins hold hormones inactive in systemic circulation and create a reservoir within the circulation that facilitates an even distribution of hormones throughout the tissue or organ.
transport protein: A protein that binds with a hormone in systemic circulation that facilitates its efficient transport.