Question

In a population of 10,000 people, 4897 have blood type MM, 4210 have blood type MN, and 893 have blood type NN. What are the allele frequencies and the genotype frequencies for this population?

Answer 1

Frequency of genotype MM in the given population= 0.4897

Frequency of genotype MN in the given population= 0.421

Frequency of genotype NN in the given population= 0.0893

Frequency of allele M =0.7002

Frequency of allele N =0.2998

Explanation:

Frequency of genotype MM in the given population= 4897/ 10000= 0.4897

Frequency of genotype MN in the given population= 4210/ 10000= 0.421

Frequency of genotype NN in the given population= 893/ 10000= 0.0893

Frequency of allele M in the given population= total number of MM individuals x 2 + total number of MN individuals/ 10000 x 2 =

4897 x 2 + 4210 / 10000 x 2 = 9794 + 4210/ 20000= 14004/ 20000= 0.7002

This is because each individual with MM genotype has two copies of M alleles while the ones with MN genotype have one copy of M allele.

Likewise, Frequency of allele N in the given population= total number of NN individuals x 2 + total number of MN individuals/ 10000 x 2 = 893 x 2 + 4210 / 10000 x 2 =5996/ 20000=0.2998

This is because each individual with an NN genotype has two copies of N alleles while the ones with MN genotype have one copy of the N allele.