Answer:
Endorphin
Step-by-step explanation:
Endorphins are peptide hormones produced by the body notable for relieving pain and stress. It decreases the feelings of pain, enhance immune response and modulate appetite.
Endorphins are referred to as natural painkillers and they are similar in structure to morphine drugs which are opiods.
Despite the Jose's twisted ankle, he didn't notice the pain and hence kept on playing the soccer game because his endorphin levels had spiked up or increased.