Answer:
The first reported case happened in Queens, New York in 1999.
"West Nile virus (WNV) has quickly established itself in North America since its recognition in New York City in 1999. Historically, WNV has been associated with temporally dispersed outbreaks of mild febrile illness."
West Nile Virus: An Historical Overview
James J. Sejvar
Ochsner J. 2003 Summer-Autumn; 5(3): 6–10.
PMCID: PMC3111838