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One member of the serine protease family is trypsin. Trypsin cleaves the polypeptide chain by breaking the peptide bond after a lysine (lys) or arginine (arg) amino acid. What would be the product(s) if each of the following peptide molecules were treated with trypsin?

a. leu-thr-phe-ala-ser
b. trp-tyr-lys+ala-phe
c. 2lys+2-arg-va

User Urb
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2 Answers

3 votes

Answer:

The protease Trypsin would cleave the peptide molecules in the following ways below.

Step-by-step explanation:

Each member of the serine protease family cleaves/cuts the bond after a specific amino acid of the substrate due to that specific amino acid being recognized by a binding structure of the enzyme that is specifically created to bind that specific amino acid. Therefore the protease would cleave the following peptide molecules in the following ways:

  1. leu-thr-phe-ala-ser would remain unaffected by the protease trypsin as lysine and arginine amino acids to not form part of the peptide molecule.
  2. trp-tyr-lys-ala-phe would be cleaved by trypsin and become: trp-tyr-lys + ala-phe.
  3. lys-arg-lys-arg-va would be cleaved to have a product of 2lys + 2arg +va.

User Jyshin
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3 votes

Answer is below

Step-by-step explanation:

One member of the serine protease family is trypsin. Trypsin cleaves the polypeptide-example-1
User Pedro Perez
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