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Does the presence of acid-fast organisms in a clinical specimen always suggest serious clinical disease?

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Answer: Yes

Explanation: Clinical disease is a type of disease that has a recognizable clinical signs and symptoms.

Acid- fast organism are identified using a differential staining techniques called acid-fast staining, it help differentiate between bacteria groups especially as members of the genus Mycobacterium stands out.

Mycobacterium is the cause of the clinical disease called tuberculosis.

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