Question

The Encyclopedia of DNA Elements (ENCODE) project aims to discover functional elements in DNA. One technique employed is DNase-seq. This technique employs a DNase enzyme that digests accessible regions of chromatin, while inaccessible regions remain undigested. The undigested DNA is then sequenced. Which of the following is likely true of the DNase-seg results? Choose one or more: A. Centromeric DNA is likely to be sequenced in all samples. B. The sequenced DNA will be the same from cell type to cell type. C. Unsequenced DNA regions were likely bound to nucleosomes. D. Unsequenced DNA is likely part of euchromatin.

Answer 1

A and D

Step-by-step explanation:

The Encyclopedia of DNA elements (ENCODE) is a public research project which aim to identify functional elements in the human genome. The encode is currently implemented in four phases; the pilot phase, the technology development phase, production phase and continuation which include functional characterization and further integrative analysis for the encyclopedia.