Answer:
congenital insensitivity, or when the person has or can not feel physical pain,
can effect daily life in many ways. they can die from injuries or sickness being unnoticed/ not treated properly.
Edit:
feeling pain is necesarry to live as humans. people with CIP usually die in their childhood. they can't even enjoy daily life. they can't feel anything. they have to stay inside mostly, also, because the outdoors can cause many dieseases.