Answer:
The issue may be related to the Operating System (OS) or a driver working abnormally.
Step-by-step explanation:
The application that does not work properly may be due to some corrupt core files in the OS that are required for the application to work as due. It could also be that a service needs to be stopped for the application to work properly.
When in safe mode, only important services and system programs are allowed to run. So, it could be that service affecting the smooth performance of the application is not running in safe mode.