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What was the greatest challenge for both american settlers and the American Indians in the west in the mid-1800s

User Timje
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Answer:

he greatest challenge for both American settlers and American Indians in the West in the mid-1800s was a)the exposure to harsh weather. Many settlers and pioneers had to go against harsh weather conditions, such as gales, arid desert conditions and long winters

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User Dirck
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Answer:

Threat to deady dieseses

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B

User Clorz
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