Answer: b) History of nonsteroidal anti-inflammatory drug (NSAID) use
c) Epigastric pain that is relieved by antacids
d) Nausea and weight loss
Step-by-step explanation:
Peptic ulcer disease can be defined as the disease which results in painful sores or ulcers in the stomach lining or in the small intestine. It is characterized by the symptoms of melena, hematemesis, nausea, weight kiss and epigastric pain on the left side of the abdomen develop after 1 to 2 hours of eating and this can be relieved through antacids.
The use of NSAID is associated with the peptic ulcer disease. The NSAID is responsible for inhibition of the COX-1 gene in the gastrointestinal tract that leads to the reduction in the secretion of prostagladin as a result of this gastric mucosa becomes susceptible to injury.