Answer:
A. 2,3 BPG
Step-by-step explanation:
2,3-bisphosphoglycerate (BPG), otherwise known as 2,3-DPG, enables the transition of hemoglobin from a very high-oxygen-affinity state to a reduced-oxygen-affinity state.
Tissues hemoglobin oxygen affinity is reduced by numerous physiological factors including.
1. Temperature Increased,
2. Carbon dioxide,
3. Acid and
4. 2,3-Bisphosphoglycerate (2,3-BPG)
all of which can contribute to decrease the oxygen affinity of hemoglobin which favours unloading and increased oxygen availability to our body cells.