Answer:
During the Age of Discovery, conquistadors sailed beyond Europe to the Americas, Oceania, Africa, and Asia, conquering territory and opening trade routes. They colonized much of the world for Spain and Portugal in the 16th, 17th, and 18th centuries.
After the Spanish discovery of the West Indies in 1492, the Spanish, primarily nobles from the west and south of Spain, began building up an American empire in the Caribbean, using islands such as Cuba, Puerto Rico, and Hispaniola as bases. From 1519 to 1521, Hernán Cortés waged a campaign against the Aztec Empire, ruled by Moctezuma II. From the territories of the Aztec Empire conquistadors expanded Spanish rule to northern Central America and parts of what is now southern and western United States and from Mexico sailing the Pacific Ocean to the Philippines. Other conquistadors took over the Inca Empire after crossing the Isthmus of Panama and sailing the Pacific to northern Peru. As Francisco Pizarro subdued the empire in a manner similar to Cortés other conquistadores used Peru as base for conquering much of Ecuador and Chile. In Colombia, Bolivia, and Argentina conquistadors from Peru linked up with other conquistadors arriving more directly from the Caribbean and Río de la Plata-Paraguay respectively.
Conquistadors founded numerous cities, many of them on locations with pre-existing pre-colonial settlements including Manila and the capitals of most Latin American countries. Besides conquests, Spanish conquistadors made significant explorations into the Amazon Jungle, Patagonia, the interior of North America, and the discovery and exploration of the Pacific Ocean.