Question

Choose the most appropriate reagent(s) for the conversion of propyne and 2-methyl-1-tosyloxypropane to 5-methyl-2-hexyne. NaNH2, NH3 NaOH, H2O KOCH2CH3, HOCH2CH3 H2SO4 NH3

Answer 1

NaNH2, NH3

Step-by-step explanation:

Choose the most appropriate reagent(s) for the conversion of propyne and 2-methyl-1-tosyloxy propane to 5-methyl-2-hexyne. NaNH2, NH3 NaOH, H2O KOCH2CH3, HOCH2CH3 H2SO4 NH3

answer is NaNH2, NH3

NaNH2, NH3 is strong to to convert propyne into a nucleophilic salt which in turn displaced tosylate in 2-methyl-1-tosyloxy propane to yield 5-methyl-2-hexyne.

Propyne and 5-methyl-2-hexyne. are still of the same homologous series,, so no triple bond is broken during the reaction

The essence of a reagent is to bring the reaction to its end point