Answer: pituitary gland
Explanation: In an oophorectomy procedure as both ovaries were removed due to which hypothalamus, pituitary and ovarian axis mainly damaged. When ovaries removed than LH (luteinizing hormone) and FSH ( follicle stimulating hormone) level increased by the pituitary gland. The hormones that are produced by ovaries also decrease in which estrogen and progesterone level decreased which cause list of problems in females.