Answer: The statement is true
Step-by-step explanation:
The sickle-cell disease is characterized by red blood cells with sickle shape (like a semi-circle). The iron-containing pigment, HEMOGLOBIN in these sickle-shaped red blood cells is
- inefficient in transporting oxygen
- likely to break down in environment with low oxygen concentration.
Such abnormally shaped red blood cells block the cavities of small blood vessels like CAPILLARIES, hindering the free movement of healthy, normal oxgen-carrying blood in them.