Question

Water-soluble hormones affect target cells by binding to __________. View Available Hint(s) Water-soluble hormones affect target cells by binding to __________. adenylate cyclase cytoplasmic receptors plasma membrane receptors cAMP protein kinases

Answer 1

plasma membrane receptors

Step-by-step explanation:

Water-soluble hormones such as amine and peptide hormones cannot cross the hydrophobic core of the plasma membranes of their target cells. Therefore, these hormones have cell surface receptors present on the surface of their target cells. Binding of water-soluble hormones to their respective plasma membrane receptors on the target cells stimulates the generation of a second messenger which in turn brings about the desired changes in the cells.

For example, binding of some water-soluble hormones to their plasma membrane receptors stimulates the formation of cAMP inside the target cells. The cAMP serves as the second messenger and activates the protein kinases which in turn activate cellular proteins involved in the generation of the desired response.