Answer:
The correct answer is - water molecules.
Explanation:
The formation of protein folding or lipid bilayer leads to the decrease in the entropy of the bilayer or protein components which is balanced by the large increase in the entropy of water molecules present around the protein or bilayer.
Nature of the protein folding plays an important role as these molecules are hydrophobic as they interact with the water molecules and water molecules become more ordered so the hydrogen bonding increase which ultimately increases in the entropy.
Thus, the correct answer is - water molecules.