Question

Choose the best answer from the list below. The NADPH used in the reductive steps of fatty acid biosynthesis comes from:

1. NADPH is generated as citrate is is converted to pyruvate in the cytosol.
2. the conversion of glucose-6-P to ribulose-5-P in the pentose phosphate pathway.

Answer 1

The correct answer is option - 1 and 2.

Step-by-step explanation:

Fatty acid biosynthesis is the formation of fatty acid from NADPH acetyl CoA with the help of the fatty acid synthases enzyme. For the biosynthesis of fatty acid, NADPH is an essential substrate that comes from the conversion of glucose-6- P into ribulose-5-phosphate in the pentose phosphate pathway.

The other source of the NADPH is by the conversion of the citrate into the pyruvate in the cytosol of the cell.

Thus, the correct answer is - option 1 and 2.