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Which action(s) could contribute to the positive inotropic effect of digoxin on cardiac myocytes?

1 Answer

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The question is incomplete as it lack the options. The multiple options are as follows;

I. Decrease transport of Ca2+ to the extracellular environment.

II. Increase availability of intracellular Ca2+ to bind to troponin.

III. Increase overall Ca2+ stores in the sarcoplasmic reticulum.

A.II only

B.III only

C.I and II only

D.I, II, and III

Answer:

I, II, and III.

Step-by-step explanation:

Digoxin is the drug used for the treatment of the heart failure patients. This drug is also used for the proper regulation of the heart beat and maintains the individual ability of walk.

The digoxin shows the positive effect on the cardiac myocetes. This drug decreases the calcium transport in the extracellular fluid and increases the intracellular calcium level that binds to troponin. This drug also increases the stored calcium level of the sarcoplasmic reticulum. These steps will helps in the contraction of the heart cells and increase the calcium level.

Thus, the correct answer is option (D).

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