Answer:
Students will clarify whatever this soliloquy indicates about the role and state of mind of Lady Macbeth. We might say, for instance, that Lady Macbeth isn't as pleased regarding her husband becoming king as she had anticipated.
She is aware that they're still in a threatening situation. Killing Duncan helped bring them their urge (power) yet it did not make them "content" or bring them "safety." Students can also keep in mind that her claim that destruction is safer than destroying and feeling insecure shows how upset Lady Macbeth is.