Final answer:
To simplify the expression, use the rules of exponents to subtract the exponents for p, q, and r.
Step-by-step explanation:
To simplify the expression, we can use the rules of exponents. When dividing with the same base, we subtract the exponents. In this case, p is raised to -4 in the numerator and -3 in the denominator, resulting in p-4 - (-3) = p-1. Similarly, q is raised to 5 in the numerator and -2 in the denominator, resulting in q5 - (-2) = q7. And r is raised to 6 in the numerator and 1 in the denominator, resulting in r6 - 1 = r5.
Therefore, the simplified expression is p-1q7r5.