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A researcher introduces double-stranded miRNA into a culture of mammalian cells and can identify its location or that of its smaller subsections experimentally, using a fluorescent probe. Sometime later, she finds that the introduced miRNA separates into single-stranded RNAs, one of which is degraded. Use this information to answer questions 1 and 2.

1. What does this enable the remaining strand to do?

A.bind to noncomplementary RNA sequences
B.combine with a signal recognition particle (SRP) blocking translation
C.attach to histones in the chromatin
D.activate other miRNAs in the cell
E.bind to complementary regions of target mRNAs

2. When she finds that the introduced miRNA separates into single-stranded RNAs, what other evidence of this single-stranded RNA activity can she find?
A.The rate of accumulation of the polypeptide encoded by the target mRNA is reduced.
B.She can measure the degradation rate of the remaining single strand.
C.The cell's translation ability is entirely shut down.
D.The amount of miRNA is multiplied by its replication.
E.Both A and B are correct

User Siefca
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1 Answer

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Answer:

E.bind to complementary regions of target mRNAs

A.The rate of accumulation of the polypeptide encoded by the target mRNA is reduced.

Step-by-step explanation:

A researcher introduces double-stranded miRNA into a culture of mammalian cells and can identify its location or that of its smaller subsections experimentally, using a fluorescent probe. Sometime later, she finds that the introduced miRNA separates into single-stranded RNAs, one of which is degraded. Use this information to answer questions 1 and 2.

microRNAs (miRNAs) are a class of ∼22-nt noncoding RNAs(Ribonucleic Acids) that regulates gene expression in plants and animals. Precursor miRNA hairpins are mostly cut by Dicer in the cytoplasm to manufacture a double-stranded. when a double stranded miRNA separates into single stranded RNAs it is actually that it is attached to the complementary region of target mRNA

When she finds that the introduced miRNA separates into single-stranded RNAs, what other evidence of this single-stranded RNA activity can she find?

it means that:

The rate of accumulation of the polypeptide encoded by the target mRNA is reduced.

User Jaclynn
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