Answer:
The correct answer is option C.
Step-by-step explanation:
Isoleucine and Valine both are amino acids that are branched, aliphatic and carrying aliphatic chain with alpha amino and alpha carboxylic acid group. These are presented within the protein.
As both are aliphatic and hydrophobic in nature so there would be no major effect on the particular protein due to the amino acid replacement. In the case of the in aromatic or aliphatic and hydrophobic and hydrophilic amino acids replacement most likely to get major structural changes in the protein.
Thus, the correct answer is - Option c.