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In apoptosis thecell destroys itself from

within and avoids leakage of the cellcontents into the
extracellular space. Whatmight be the consequences if programmed
cell death were notachieved in so neat and orderly a fashion?

User AzraelAT
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1 Answer

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Answer and explanation:

One of the unordered forms of the dying cell is necrosis.

Necrosis is caused by lesions that impede internal balance control: water and some ions, especially sodium and calcium, normally pumped out, flow freely into the swelling and rupturing cell. The necrosis rupture releases into the surrounding tissue cellular content, rich in proteases, enzymes that "cut" other proteins, and other toxic substances. In addition to direct toxicity to neighboring cells, the stroke generates substances that attract immune cells, causing an intense inflammatory reaction: some types of white blood cells, especially neutrophils and macrophages, converge to necrosis tissue and ingest dead cells. Inflammation, typical of necrosis, is important for limiting infections and removing cell debris, but white blood cell activity and secretions can also damage neighboring, sometimes devastating, normal tissues.

User Zach Leighton
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