Question

A group of nursing students are reviewing the pain-relieving action of NSAIDs. The students demonstrate understanding of the information when they identify which actions as being blocked to achieve pain relief?

Answer 1

The blocking of the activity of cyclooxygenase- 2.

Explanation:

The NSAIDs or nonsteroidal anti-inflammatory drug mainly prevents COX-2 or cyclooxygenase-2 enzymes from functioning. The NSAIDs are generally a group of medicines, which relieve fever and pain and minimize inflammation. The COX-2 enzymes are accountable for discharging prostaglandins post-injury or after infection.

The prostaglandins exhibit many different effects, of which one is to monitor inflammation. By mainly preventing COX-2 enzymes, the NSAIDs relieve pain and inflammation with less harmful gastrointestinal effects.