Question

The nursing instructor is talking with the junior nursing class about migraine headaches. What would the instructor tell the students is the method of action of Sumatriptan?

A. Vasoconstrictive on cranial blood vessels
B. Works at the site of the migraine to eliminate pain
C. Dulls the perception of pain in the brain
D. Causes vasodilation of cranial blood vessels

Answer 1

A. Vasoconstrictive on cranial blood vessels

Step-by-step explanation:

Sumatriptan is a sulfonamide triptan with vasoconstrictor activity. Sumatriptan selectively binds to and activates serotonin 5-HT1D receptors in the central nervous system (CNS), thereby constricting cerebral blood vessels. This may lead to a relief in pain from vascular headaches. Sumatriptan may also relieve vascular headaches by decreasing the release of vasoactive neuropeptides from perivascular trigeminal axons in the dura mater during a migraine, by reducing extravasation of plasma proteins, and by decreasing the release of other mediators of inflammation from the trigeminal nerve.

Answer 2

The correct answer is option A.

Step-by-step explanation:

Sumatriptan is medication or the drug that belongs to the class of drugs called triptans. Sumatriptan affects the particular natural chemical or substance such as serotonin.

The effects on the serotonin of the sumatriptan leads to the vasoconstriction of the cranial blood vessel in the brain that help in reducing the headaches. Vasoconstriction is the narrowing of the blood vessels,

Thus, the correct answer is - option A.